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为解决放疗后肝损伤 (RILD)的代谢紊乱难题,台湾长庚纪念医院团队通过1H NMR代谢组学技术,揭示了牛磺酸在辐射诱导肝病中的动态保护机制。研究发现急性期牛磺酸水平升高而慢性期降低,补充牛磺酸可显著改善肝功能指标 (AST/ALT)并抑制纤维化进程,为临床防治非经典RILD提供了新靶点。
编辑推荐: 【编辑推荐】本研究通过生长指标测定、光合色素分析、抗氧化酶活性检测及1H NMR(核磁共振)代谢组学技术,系统揭示了大豆(Glycine max)幼苗对镉(Cd)、铅(Pb)胁迫的代谢重编程机制。3 mM Cd导致根长锐减93.5%,5 mM Pb使SOD(超氧化物歧化酶)活性激增163.3%,并鉴定出34种关键代谢物 ...
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News-Medical.Net on MSNStudy shows promising anti-diabetic potential of coffee's functional components
Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion.
The 4.0 mm triple resonance (1H, 13C, 15N) E-free CPMAS Bio-solids probe is used for experiments on solid biological samples. Anasazi Eft-60 NMR Probes There is one probe available for the Anasazi Eft ...
During the 1970s, two-dimensional NMR was discovered and rapidly evolved NMR into the powerful tool that it is today for molecular structural determination. Two-dimensional NMR spectra have two ...
Signals for water occur at different frequencies in 1 H NMR spectra depending on the solvent used. Listed below are the chemical shift positions of the water signal in several common solvents. Note ...
1 H NMR reveals inter-hemispheric effects of cerebral ischemia 1 H nuclear magnetic resonance (1 H NMR) spectroscopy was employed to concurrently evaluate the amounts of various metabolites.
Bacterial and fungal genomics and natural product mining. The BrisSynBio 700 MHz instrument has a state-of-the-art 1.7mm cryo-enhanced probe and offers some of the highest sensitivities for 1 H NMR in ...
qNMR Using PULCON Use this document to perform quantitative NMR (qNMR) experiments using the PULCON methodology. This technique allows you to obtain concentration information about your NMR sample ...
60 MHz 1H NMR spectrum of MDMA crystal sample in DMSO-d6, containing ethylene carbonate (EC) and D2O. The integration areas of the methylene signal (1) for MDMA and resonance (2) for EC were ...
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