The zebrafish, a well-established model organism in basic biomedical research, has also become tractable for numerous applications in drug discovery, from phenotypic screens to testing for ...

The zebrafish has emerged as an important model system with which to investigate cancer, particularly for validating genomics data and for undertaking screens for oncogenes and drivers of tumour ...

Researchers identified that two cyclin D genes, ccndx and ccnd2a, independently regulate distinct stem and progenitor cell ...

This is a well-written study that presents a solid genetic screen to identify regulators of adipose morphology and remodeling in zebrafish. The authors generated a rigorous screening platform based on ...

Scientists discover zebrafish hair cells can regenerate without cell division, challenging decades of textbook biology and ...

Humans are a suggestible species. We see a friend yawn, we yawn. We see a stranger yawn, we yawn. We see an animated blob do something resembling yawning, we yawn. Heck, there’s a fair chance you’re ...

Zebrafish have the rare ability to regenerate their heart muscle after major damage, unlike humans. Researchers have now discovered the gene circuit that accomplishes this — an embryonic circuit that ...

Scientists have discovered how two genes control the regeneration of sensory hair cells in zebrafish, a process that fish ...

A section of liver tumour in a zebrafish shows liver cell DNA (cyan), cancer cells with KRAS activity (purple), and DNA damage (white). The study found that lowering a key protein involved in minor ...

Zebrafish were partly chosen for the research because around 80% of genes associated with human diseases have a corresponding orthologue -- a gene in a different species that evolved from a common ...

Zebrafish and humans share 70% of the same genes. "We can see exactly what's happening while it's happening in zebrafish providing us with insight for human embryonic development," says Zinani.

Zebrafish, like the adult seen here, seem to experience sleep cycles that are similar to REM sleep in humans, according to a new study that looked at neural activity in the tiny aquatic animals.