Jonathan Parkinson, Ryan Hard, Wei Wang. The RESP AI model accelerates the identification of tight-binding antibodies. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-36028-8 ...

That insight led the team to make cresomycin’s 10-membered ring. Structural biology studies show that cresomycin binds tightly to several bacterial ribosomes, including drug-resistant ones.

ACE2.v2.4 has already been shown to tightly bind every VOC in cell-based assays and to neutralize the original virus in mouse studies.

The major difference is that the existing decoy closely resembles the natural ACE2 receptor, and has not been mutated to bind as tightly as possible to SARS-CoV-2, while sACE2.v2.4 has.

In tests in rats and pig tissues, the researchers showed that their new tape can tightly bind tissues such as the lungs and intestines within just five seconds. They hope that this tape could ...