Dendritic cells (DCs) are required for the induction of cytotoxic T cells (CTL). In most tissues, including the lung, the resident DCs fall into two types expressing the integrin markers CD103 and ...

The study highlights T-bet's importance in memory B cells, essential for rapid antibody production and sustained immune defense against influenza.

Researchers have mapped the complex landscape of cytotoxic T lymphocytes (CTLs), revealing how their remarkable diversity and adaptability influence cancer immunotherapy outcomes. This comprehensive ...

Researchers describe six subsets of memory B cells — including one subset that produces the transcription factor T-bet. Using detailed genetic analysis and manipulation, they show that continuous ...

Moreover, the fact that proteinase 3–ANCA and myeloperoxidase-ANCA polyangiitis have distinct genetic causes suggests that clinical trials that have considered ANCA-associated vasculitis as a ...

Based on data from 59 patients, we calculated for each day after PBSC transplantation the dose of CD34+ cells that resulted in rapid recovery of either neutrophils or platelets in the majority (> 70%) ...

Computational algorithms for selecting subsets of regression variables are discussed. Only linear models and the least-squares criterion are considered. The use of planar-rotation algorithms, instead ...

Background: The tumor microenvironment provides important insights into cancer behavior and its response to treatment. In particular, the cellular composition and spatial arrangement of tumor immune ...

Results are obtained which given an upper bound on the number of compact subsets of a topological space in terms of other cardinal invariants. The countable version of the main theorem states that an ...