In a study known as CROWNS-2 published in JAMA, the researchers randomly assigned 180 adults with CRSwNP to stapokibart (300 ...

In the CPS-10 subgroup, a confirmed objective response occurred in 116 of 220 patients (52.7%) in the pembrolizumab–chemotherapy group and in 42 of 103 (40.8%) in the placebo–chemotherapy group.

Data from these subgroup analyses are consistent with results from the main CLEAR Outcomes analysis, which showed a 13% reduction in the relative risk of major adverse cardiovascular events ...

"HMNC focuses on MDD subgroup following efficacy signal in Phase IIb trial" was originally created and published by Clinical ...

ITM Isotope Technologies Munich SE (ITM), a leading radiopharmaceutical biotech company, today announced that further data on ...

The subgroup analysis presented here is a histology-driven analysis of a large, prospective, randomized phase III trial that was conducted in patients with advanced LPS or LMS. In this trial, 452 ...

In a subgroup analysis involving women who had not received tamoxifen previously, the median overall survival was 40.3 months in the anastrozole-alone group, as compared with 52.2 months in the ...

In the presence of treatment heterogeneity due to unknown grouping information, standard methods that assume homogeneous treatment effects cannot capture the subgroup structure in the population. To ...

Medulloblastoma is a highly malignant paediatric brain tumour, often inflicting devastating consequences on the developing child. Genomic studies have revealed four distinct molecular subgroups ...

Subgroup analyses are important elements of clinical trial results reporting. Only average results are reported in RCTs, and trial participants are frequently recruited from a heterogeneous population ...

We prove that the computational problem of auditing subgroup fairness for both equality of false positive rates and statistical parity is equivalent to the problem of weak agnostic learning — which ...