To study the stereoselectivity of satropane (3-paramethylbenzene sulfonyloxy-6-acetoxy tropane), a novel tropane analog, on iris muscarinic receptor activation and intraocular hypotension. The ...

Antibody drug conjugates remain a niche, but strong area of investment. In the first project, the researchers designed an intramolecularly assisted catalyst for the synthesis of beta-amino acids.

Success in simple creation of artificial metalloenzymes with high stereoselectivity Opens mechanistic study of natural enzymes Peer-Reviewed Publication Osaka Metropolitan University ...

Enzymes, meanwhile, are superstars of stereoselectivity—but there’s only one enzyme that naturally works with fluorinated substrates. Fortunately, it’s possible to teach old enzymes new tricks.