撰文丨王聪编辑丨王多鱼排版丨水成文抗生素的发现让我们有了战胜致病菌的有力武器，挽救了无数生命。然而，抗生素的广泛应用也带来了一个巨大的危机——抗生素耐药性（AMR），据《柳叶刀》发布的最新全球细菌耐药性负担数据，2021 年全世界有 471 ...

A National Institutes of Health (NIH)-supported clinical trial has found that the outcome of treating complicated ...

A new way to battle bloodborne staph infections could help save lives while combating the rise of antibiotic-resistant ...

推荐：针对金黄色葡萄球菌 (Staphylococcus aureus)肺部感染缺乏人源化模型的难题，哥伦比亚大学团队开发了植入自体胎儿肺组织的人源化小鼠模型。研究发现该模型能支持细菌存活扩散，导致免疫细胞死亡且缺乏趋化因子诱导，并通过双RNA-seq揭示宿主Cyp24a1基因显著上调及细菌应激反应通路激活。该模型为研究人类特异性感染机制及抗生素耐药提供了新工具，发表于《Mucosal ...

The results of a randomized clinical trial suggest that patients with serious bloodstream infections caused by Staphylococcus ...

The two designed compounds, dubbed NG1 and DN1, effectively treated N. gonorrhoeae and S. aureus respectively in preclinical models.

With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat two hard-to-treat ...

A randomized clinical trial set up to assess if dalbavancin is superior to standard treatment for Staphylococcus aureus ...

镉暴露增强拟环纹豹蛛 (Pardosa pseudoannulata)对金黄色葡萄球菌 (Staphylococcus aureus)的易感性及其免疫抑制机制研究 《Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology》：Cadmium exposure improved the ...