2025年8月10日，北京大学/昌平实验室魏文胜团队在Nature Communications发表研究论文，基于一型与二型内含子的第二步剪接反应，开发了两种全新的体外RNA环化方法：PIET（Permuted Intron-Exon through ...

2021年5月16日讯/ 生物谷 BIOON/---选择性剪接（alternative splicing）是一种转录后调控机制，对转录组和 蛋白质组 的多样性至关重要。通过增加蛋白水平 ...

Skyhawk's RNA tech could be Merck's next blockbuster play as drug setbacks and looming patent cliffs force a reinvention.

HNF1A mutations are found to dysregulate RNA splicing in pancreatic cells, thereby contributing to the onset of diabetes.

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA ...

Merck KGaA has swooped into a neurological-focused pact with RNA biotech Skyhawk Therapeutics that could top out at $2 ...

Nature：重大进展！新研究揭示常见的SF3B1基因突变如何导致癌症 BRD9 SF3B1 剪接因子 反义寡核苷酸 基因突变 来源：本站原创 2019-10-17 13:28 2019年10月17日 ...

One such splicing neoantigen prediction, SLC45A2, has emerged as a particularly promising target due to its high tumor specificity and immunogenicity.

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that ...

Splicing has a key role in oncogenesis, tumor suppression, and metastasis in cancer-related genes. Various types of cancers have been linked to changes in alternative splicing.