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很多证据表明存在一类因子能够参与控制ZGA事件是否能被允许发生以及何时发生。 因此作者提出ZGA 许可因子 (Licensor)的概念来代表这一类因子,转录因子则作为Specifier (特异性决定因子)提供基因表达的特异性。
We predicted Gata6 as a lineage specifier of PE, which has previously been shown to induce this differentiation. 36 On the other hand, Klf2 and Nanog were predicted for EPI cell-fate specification.
In the most minimal form of x-bar theory, all branching is binary. No other kinds of domination is allowed. XP cannot dominate X alone because XP does not branch. In the simplest form, X is both a ...
The addition of the anxiety distress specifier in the DSM-5 has simplified the task of identifying those patients whose anxiety must be considered in their treatment plan, said Mark Zimmerman, MD ...
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