More information: Lingjia Kong et al, Single-cell and spatial transcriptomics of stricturing Crohn's disease highlights a fibrosis-associated network, Nature Genetics (2025). DOI: 10.1038/s41588 ...

A Bayesian decoder was employed to calculate the posterior probabilities of all position bins. This method assumes that transient counts follow a Poisson distribution and combines transient counts and ...

Researchers at the Max Delbrück Center have developed an open-source spatial transcriptomics (ST) platform, called Open-ST, that creates 3D molecular maps from patient tissue samples with ...

The model illustrates how biological function can form spatial structures—and thus generates an organ morphology that is deeply rooted in function.

Background: This study evaluates the predictive utility of an artificial intelligence (AI)-powered whole-slide image (WSI) analyzer for assessing Tumor-infiltrating lymphocytes (TILs) and tertiary ...

Spatial transcriptional dynamics of CD74⁺ B cells in tertiary lymphoid structures and effects on immune evolution in penile squamous cell carcinoma.. JCO 43 , 5038-5038 (2025). DOI: ...