针对肾脏替代疗法 (KRT)是否影响危重患者间接测热法 (IC)测量准确性的问题，德国莱比锡大学医院团队开展前瞻性研究，纳入100例机械通气AKI患者，对比CVVHD（枸橼酸抗凝）与SLEDD（肝素抗凝）治疗期间的IC参数。结果显示两种KRT模式均未显著改变静息能量消耗 (REE)、氧耗量 (VO2)或CO2产量 (VCO2)，为ICU精准营养支持提供了重要循证依据。

更麻烦的是，SLEDD 会影响美罗培南的药代动力学过程。由于美罗培南分布容积小、分子量低且蛋白结合率低，SLEDD 治疗过程中，药物浓度波动大，治疗时浓度可能过低影响疗效，不治疗时浓度又可能过高增加毒性风险。目前，针对重症 SLEDD 患者使用美罗培南的最佳给药方案，相关研究有限且建议不 ...

Sledd’s parents couldn’t be reached for comment on the Pentagon announcement of al-Fadhli’s death. Sledd, whose fraternal twin, Mike, was serving in the corps when his brother died, sent his ...

Stacey Sledd DeMoss checks on sunn hemp blooms in the crop maze with her daughter, Makayla DeMoss, 11, at Sledd's U-Pick Farm in Mims on Friday, Sept. 14, 2018.

Sledd, who lives in Richmond, is a former chief executive officer of Performance Food Group and now is a managing partner of Pinnacle Ventures. "He's a Fortune 500 business leader," McDonnell said.

Sledd, 44, shuns the limelight, preferring instead to talk about how others at Performance have made their mark. "It's not an ego thing for me like it is for others," Sledd said.

Sledd succeeds P. Cody Phipps, who was chairman, president and CEO of Owens & Minor since 2015, after previously serving as president and CEO of United Stationers Inc., a Deerfield, Ill.-based ...