研究人员针对日益严峻的细菌耐药性问题，对皂苷元 (sapogenins)及其衍生物展开抗菌机制研究。通过修饰C-3位点合成系列化合物，发现伪薯蓣皂苷元 (pseudo-diosgenin)和 (25R)-5α-螺甾烷-3β基-L-谷氨酸酯对大肠杆菌 (E. coli)具有显著抑制效果，而 (25R)-螺甾-5-烯-3β基吡啶-3-羧酸酯对铜绿假单胞菌 (P. aeruginosa ...

Tessa Moses, Jacob Pollier, Lorena Almagro, Dieter Buyst, Marc Van Montagu, María A. Pedreño, José C. Martins, Johan M. Thevelein, Alain Goossens, Combinatorial biosynthesis of sapogenins and saponins ...

Interdisciplinary in scope, Economic Botany bridges the gap between pure and applied botany by focusing on the uses of plants by people. The foremost publication of its kind in this field, Economic ...

THE relatively simple method of analysis recently described by Wall, Eddy, McClennan and Klumpp 1 for the analysis of plant samples for steroidal sapogenins inspired me to search for them in the ...