Total neoadjuvant therapy demonstrates consistent real-world efficacy across regimens in patients with locally advanced ...

Young Americans born in 1990 now face a fourfold higher rectal cancer risk than those born in 1950. Discover the lifestyle factors and health disparities fueling this trend.

导语据我国癌症中心最新数据统计，结直肠癌已成为我国第二大高发恶性肿瘤，2022 年新发病例达 51.71 万例，死亡病例达 24 万例[1]。在新发结直肠癌病例中，近半数（49.8%）为直肠癌[2]，且直肠癌早期临床表现隐匿，近 60% 的患者确诊时即为局部晚期直肠癌（locally advanced rectal ...

A recent meta-analysis reveals no link between pathologic complete response and long-term survival in rectal cancer, challenging its use as a surrogate endpoint.

A new large-scale study has found that Americans born in 1990 face four times the risk of developing rectal cancer compared to those born in 1950, sounding alarms about rising early-onset ...

A recent study reveals a concerning rise in early-onset colorectal cancer, particularly among those born in 1990, who face a ...

Medically reviewed by Gagandeep Brar, MD When cancer cells develop in the rectum, they can cause symptoms like changes in bowel habits, blood in your stool, unintentional weight loss, fatigue, and ...

Medically reviewed by Kumkum S. Patel, MD Medically reviewed by Kumkum S. Patel, MD Rectal cancer is cancer that originates in the tissues of the rectum. This type of cancer is sometimes referred to ...

Although the term locally advanced rectal cancer (LARC) is often used, an international consensus on the definition is still lacking. Definitions vary from tumor growth into the mesorectal fat ...

Rectal bleeding is a recognised early symptom of colorectal cancer. This study aimed to assess the diagnostic accuracy of symptoms, signs and diagnostic tests in patients with rectal bleeding in ...

Rectal cancer research at MSK and elsewhere shows that watch and wait for localized rectal cancer appears to be just as safe as surgery to remove the rectum. These studies include a new analysis of ...

Rectal prolapse causes significant discomfort because of the sensation of the prolapse itself, the mucus that it secretes, and because it tends to stretch the anal sphincters and cause ...