Cyclin-dependent kinase 5, a serine/threonine kinase, contributes to neurodegeneration in Parkinson's disease. This kinase is now shown to phosphorylate peroxiredoxin-2, inactivating it, and ...

Five-membered heterocycles are among the broadest class of organic compounds. Major sub-classes of these compounds are imidazole, isoxazole, pyrazole, oxazole, tetrazole, thiazole, triazole, and other ...

Laser Pulse,Ag Nanoparticles,Argon Atmosphere,Average Size Distribution,Bacterial Growth,Band Gap,Carrier Dynamics,Carrier Lifetime,Carrier Mobility,Changes In ...

2019 National Council of Undergraduate Research - Chemistry Division's Outstanding Research Mentorship Awardee. 2022 Outstanding Four-Year College and University Chemistry Teaching Award from the New ...

The team identified a promising lead in family of small molecules, the pyrazole resorcinol series, and helped to demonstrate the practicality of targeting Hsp90 as a strategy for defeating cancer.

I completed my PhD in the protein and nucleic acid biochemistry lab at The University of Sheffield where my work involved studying the mechanism of DNA methylation. My project involved exploring the ...

Metabolic differences among and within tumors can be an important determinant in cancer treatment outcome. However, methods for determining these differences non-invasively in vivo is lacking. Using ...

Research efforts in the Lemaire group are very multi-faceted. In general terms, we are interested in the preparation and properties of new hybrid inorganic/organic materials. This work encompasses ...