研究背景与科学挑战 化脓性链球菌（S. pyogenes）每年导致50万人死亡，其中低收入地区风湿性心脏病（RHD）是主要死因。 疫苗研发的核心障碍在于对自然保护性免疫机制的认知不足，尤其是针对咽喉炎和脓皮病的免疫保护。

Streptococcus pyogenes infections are a major cause of morbidity and mortality worldwide with an estimated 500,000 deaths, most of which are attributable to invasive infection, acute rheumatic ...

Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface. Cell Reports, 2021; 34 (13): 108924 DOI: 10.1016/j.celrep.2021.108924 ...

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis ...

BUFFALO, N. Y. – Numerous scientific studies have concluded that two common bacteria that cause ear infections, strep throat and more serious infections cannot live for long outside the human body. So ...

A new study looked at the genes of hundreds of S. pyogenes samples from Japan and other countries to pinpoint the genetic differences that make some strains more dangerous. The research group ...

Osaka, Japan - Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses ...

S. pyogenes bacteria causes severe infections, including necrotizing soft tissue infection (NSTI), an illness characterized by an excessive inflammatory response that could be life-threatening and ...

Asymptomatic strep throat, where individuals carry the bacteria Streptococcus pyogenes in their throats without experiencing symptoms, is a well-documented phenomenon, particularly among children.

A 54-year-old man presented with gangrenous myositis caused by Streptococcus pyogenes. A review of the literature disclosed 10 similar cases. Their presenting manifestations were spontaneously ...