Theoretically, some pseudogenes may be transcribed, and the RNAs produced may have some gene regulatory functions, as mentioned earlier. However, we currently have no evidence to suggest that this ...

Pseudogenes are segments of DNA that once encoded proteins but have since lost their ability to do so due to sequence degradation — a phenomenon referred to as devolution. Here, devolution represents ...

More by Mark Gerstein and Deyou Zheng This article was originally published with the title “The Real Life of Pseudogenes” in Scientific American Magazine Vol. 295 No. 2 (August 2006) ...

The first pseudogene was discovered in 1977 and, until very recently, pseudogenes were thought to be irrelevant byproducts of evolution scattered throughout the genome. Pseudogenes are introduced into ...

The physical and evolutionary energy landscapes of devolved protein sequences corresponding to pseudogenes. Proceedings of the National Academy of Sciences, 2024; 121 (21) DOI: 10.1073/pnas.2322428121 ...

However, since current aligners lack the sensitivity to distinguish reads that come from homologous parts of the genome, it is a challenge to work with genes with paralogues or pseudogenes.

Liang's study is novel in that understanding of pseudogenes relies on analyzing large numbers of patient samples. Previous studies have been limited by the size of the patient sample groups.

Pseudogenes: dysfunctional, unloved and seemingly of little use, these poor-cousin relatives of genes have lost their protein-coding abilities. They contain material not essential for an organism ...

The central dogma of molecular biology, as proposed in 1970 by Francis Crick and James Watson, holds that genetic information is transferred from DNA to functional proteins by way of messenger RNA ...

The study by researchers at MD Anderson Cancer Center raises the possibility of using the information provided by these dysfunctional genes. Alas, the thankless pseudogene. Dysfunctional, unloved ...

Pseudogenes are like broken-down copies of normal genes. They look similar to regular genes, but they don’t work properly because they’ve lost the ability to produce functional proteins.