A prothrombin time test tells you how long it takes your blood to clot. Learn what it looks for, when you might need one, and what the results mean.

Prothrombin gene mutations are most common among people of European ancestry. Heterozygous mutations affect 2% to 4% of people with this background, according to the National Blood Clot Alliance.

Prothrombin gene mutation is diagnosed with a blood test. A sample of your blood is sent to a laboratory and the DNA is analyzed to determine if the mutation is present.

Prothrombin Complex Concentrate（PCC）对比 Frozen Plasma 治疗心脏手术中凝血病性出血的多中心随机临床试验：FARES-II 研究 《JAMA》：Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: The ...

More information: Keyvan Karkouti et al, Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery, JAMA (2025). DOI: 10.1001/jama.2025.3501 ...

We used a PCR assay to prepare full-length human prothrombin complementary DNA (cDNA) obtained from a human liver cDNA library (Clontech) and cloned this into pcDNA TM 3.1 (+) (Invitrogen) to ...

Warfarin-induced coagulopathy can be reversed faster with a weight-based factor VIII inhibitor bypassing activity regimen than with fresh frozen plasma, researchers report, but mortality is similar.

Venous thromboembolism (VTE) is a well-recognized complication of cancer. Laboratory parameters might be useful to assess the VTE risk in patients with cancer. The aim of this study was to investigate ...

Decreases in the prothrombin-time improvement paralleled the decreasing levels of factors II, VII and X. Repeated fresh plasma transfusions at four and eight hours after the initial transfusion ...

A concentrated form of prothrombin complex appears to rapidly and permanently reverse the effects of the novel anticoagulant rivaroxaban, a factor Xa inhibitor. But according to results of a small ...