The third-generation thienopyridine P2Y 12-receptor blocker, prasugrel, has been shown to have net clinical benefits over clopidrogrel in the treatment of patients with acute coronary syndromes ...

The rate of TIMI major or minor bleeding was statistically significantly greater with prasugrel than clopidogrel in the core group (3.9 percent vs. 3.0 percent respectively, p=0.033), but not in ...

Switching from maintenance clopidogrel to prasugrel results in a further reduction in platelet function after one week, according to a new study. When patients receive a loading dose of prasugrel ...

A recent study published in BMC Nephrology evaluated the comparative effectiveness of ticagrelor/prasugrel versus clopidogrel ...

Antiplatelet therapy Prasugrel administration before angiography associated with increased bleeding risk and no benefit in NSTE-ACS patients Nature Reviews Cardiology 10, 614 (2013) Cite this article ...

13. 9% in the prasugrel group versus 16.0% in the clopidogrel group (hazard ratio [HR] for prasugrel, 0.91; 95% CI, 0.79-1.05, P =0.21) The results were similar in a secondary analysis, which also ...

Prior to the crossover phase, prasugrel was more effective in improving platelet response than clopidogrel (AUC 180.5 vs. AUC 380.5; P = 0.038). However, after patients switched agents, those changing ...

Prasugrel is approved in Germany solely in combination with ASA for patients with acute coronary syndrome (ACS), i.e. with acute stenosis of the coronary vessels, who are to undergo surgery in the ...

HOUSTON, TX — Nearly one in five patients treated with prasugrel (Effient, Lilly/Daiichi Sankyo) in the PINNACLE registry is receiving the drug inappropriately or for a nonrecommended indication ...

What does this mean for me? If you have acute coronary syndrome and are having a procedure called percutaneous coronary intervention, and your doctor thinks that prasugrel is the right treatment, you ...

What does this mean for me? If you have acute coronary syndrome and are having a procedure called percutaneous coronary intervention, and your doctor thinks that prasugrel is the right treatment, you ...