We tested a proposal that postsynaptic calcium and metabotropic glutamate receptors (mGluRs) are involved in the induction of hippocampal mossy fiber long-term potentiation (LTP)1. We found that ...

Protocol Published: 22 November 2006 Immunofluorescence in brain sections: simultaneous detection of presynaptic and postsynaptic proteins in identified neurons Edith M Schneider Gasser, Carolin J ...

A research group led by Specially appointed professor, Dr. Tatsuo Suzuki of Shinshu University's School of Medicine developed a new purification protocol for Postsynaptic density (PSD) lattice, a ...

Differences in postsynaptic plasticity Postsynaptic density (PSD) is an extremely large multi-protein complex that is responsible for positioning signaling molecules that potentiate both the long ...

Summary: New research uncovers how tau pathology spreads and damages synapses in progressive supranuclear palsy (PSP). Using ...

Journal reference: Kaizuka, T., et al. (2024) FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid–liquid phase separation.

Unfortunately, antidepressants also may bind themselves directly to postsynaptic receptors that confer side effects. Such receptors include histaminergic H 1, muscarinic, H 1 -adrenergic, and ...

(4) The neurotransmitters bind to receptor sites on ion channels in the postsynaptic membrane, causing them to open. (5) Ions flow into the postsynaptic neuron, which generates an action potential ...

Richard R. Neubig, Elizabeth K. Krodel, Norman D. Boyd, Jonathan B. Cohen, Acetylcholine and Local Anesthetic Binding to Torpedo Nicotinic Postsynaptic Membranes after Removal of Nonreceptor Peptides, ...

Decades-old assumptions about brain plasticity upended Date: June 3, 2025 Source: University of Pittsburgh Summary: Your brain doesn t just send messages through one universal route it uses ...