This review presents the latest evidence on the link between genetic single nucleotide polymorphisms and dental caries, ...

We have investigated the association of the recently identified IL6R polymorphisms with the serum levels of soluble IL-6 receptor (sIL-6R). sIL-6R is generated by shedding of the membrane-bound ...

Common single-nucleotide polymorphisms (SNPs) that are associated with blood low-density lipoprotein (LDL) or high-density lipoprotein (HDL) cholesterol modestly affect lipid levels. We tested the ...

Background: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity and may play an important role in carcinogenesis. We investigated the role of genetic ...

Background Athlete's heart as an adaptation to long-time and intensive endurance training can vary considerably between individuals. Genetic polymorphisms in the cardiological relevant insulin-like ...

Effects of Genetic Polymorphisms on the Pharmacokinetics of Calcineurin Inhibitors Kyle N. Utecht; Jon J. Hiles; Jill Kolesar Disclosures Am J Health Syst Pharm. 2006;63 (23):2340-2348. 0 ...

Malgorzata Kowalczyk, Aleksander Owczarek, Renata Suchanek, Monika Paul-Samojedny, Anna Fila-Danilow, Paulina Borkowska, Krzysztof Kucia, Jan Kowalski, Heat shock protein 70 gene polymorphisms are ...

The anti–HER-2/ neu monoclonal antibody trastuzumab has been shown to engage both activatory (fragment C receptor [FcγR]IIIa; FcγRIIa) and inhibitory (FcγRIIb) antibody receptors and FcγR ...

Specifically, common polymorphisms in the CYP2C19 gene, seen in approximately 30% of whites, 40% of blacks, and more than 55% of East Asians, 31 significantly diminish both the pharmacokinetic and ...

Additionally, the researchers analyzed the expression of NFκB and KLF2 and the effects of IL-1β on endothelial cells to understand the relationship between PAI-1 polymorphisms and COVID-19 severity.

Background: Complete or partial deficiency of the DPD enzyme due to genetic polymorphisms of the DPYD gene causes acute toxicity of fluoropyrimidines, which are widely used in combination chemotherapy ...