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Both polyene-resistant isolates had altered sterols. R1 contained an unidentified $\Delta^ {5,7}$ sterol and little, if any, ergosterol; R2 was totally lacking in $\Delta^ {5,7}$ sterols.
Polyene macrolide amphotericin B (AmB) is the first-line therapy for systemic infection because of its broad spectrum and fungicidal activity.
The polyene macrolide amphotericin B (AmB) is a widely used broad-spectrum antifungal, but its use is associated with kidney toxicity. Efforts to develop renal-sparing polyene antifungals have ...
The polymerized polyene networks have also been examined by angle resolved photoemission spectroscopy (ARPES) which indicates a metallic band dispersion evolved from the insulating paraffin films ...
"Polyene substructures are ubiquitous frameworks in many natural products and pharmaceutical molecules," said Masafumi Hirano, paper author and professor of applied chemistry at TUAT.
World Polyene Phosphatidylcholine research report covers the summary Polyene Phosphatidylcholine market dynamics, competitive analysis, and leading player’s numerous ways to sustain within the world ...
Polyene pigments are found in abundance across the animal world and are involved in most red, yellow, and orange colors. However, they are particularly vulnerable to oxidation and because of this ...
Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase. Angewandte Chemie International Edition, 2017; DOI: 10.1002/anie.201700767 ...
Discovering antifungals with novel mechanisms of action is essential in the fight against drug-resistant fungi, which pose a serious concern for public health. However, progress on new antifungals is ...
To achieve this, another structural modification was introduced whereby the C16 position was converted into a non-ionizable functional group. This resulted in a new polyene compound that extracts ...
Media Contact Yutaka Nibu [email protected] Office: 81-423-887-550 TUAT president discretionary expenses, Grant-in-Aid for Scientific Research (B) ...
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