The molecular motif 1-azaspiro[3.3]heptane may look peculiar, with its two 4-membered rings that share a single carbon. But the structure can behave like a mimic of piperidine, a popular ...

A new, two-step strategy for making substituted piperidines offers chemists a more efficient way to make these biologically relevant molecules. The method, which leverages enzymatic oxidation and ...

We have essentially created a modular approach to simplify piperidine synthesis, analogous to how palladium cross-coupling revolutionized pyridine chemistry decades ago.

A team of chemists from Scripps Research and Rice University has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study ...

Piperidine is a 1-ring heterocyclic compound formed from the polyamine cadaverine in the human intestine. Because heterocyclic compounds are routinely used in the promotion of antimicrobial treatment ...