Over the past two decades, deep brain stimulation (DBS) has supplanted lesioning techniques for the treatment of movement disorders, and has been shown to be safe and efficacious. The primary ...

Pancreatic cancer (PC) is a highly malignant disease with high aggressiveness and a dismal prognosis, which is challenging to diagnose clinically early and gains low benefit from standard therapies.

Objective: Conflicting associations have been noted between thyroid function and gestational diabetes mellitus (GDM), with indications that pre-pregnancy BMI might influence these relationships. This ...

Resistance to chemotherapy in cancer cells is mainly mediated by overexpression of P-glycoprotein (Pgp), a plasma membrane ATP-binding cassette (ABC) transporter which extrudes cytotoxic drugs at the ...

Moreover, PPIs reduce, but do not eliminate, the risk of ulcers in patients taking NSAIDs, reflecting untargeted physiopathologic pathways and a breach in the ability to sustain an intragastric pH ...

Moreover, given the physiopathologic scenario of ACS and the anti-inflammatory action of statins, it could be hypothesized that the benefit of these agents may be even higher in this subset of ...

In addition to this, marked dilation of the right ventricle was observed. TroponinT was 3667 mg/dL. A possible physiopathologic explanation could be the acute increase in right ventricular pressure ...

As in the animal models, claudin-6 was shown to be implicated in dermatitis and age-related skin barrier dysfunctions; our study provides proof that a new target could be envisaged for ...

The ballistocardiograms of 13 of 14 patients with "pure" mitral stenosis were found to show acharacteristic late diastolic and early systolic deformity. The deformity consists of a footward wave which ...

The findings suggest that the gut microbiome directly affects the ECS, possibly influencing ECS signaling and subsequent physiopathologic functions.9 Cannabis, Gut Bacteria, and Neurodegenerative ...

J Am Coll Cardiol. 2005;46:2013-2017. 3. Burzotta F, Trani C, De Vita M, et al. A new operative classification of both anatomic vascular variants and physiopathologic conditions affecting transradial ...