WHEN preparing trisodium phosphorothioate from thiophosphoryl chloride and sodium hydroxide at 80° according to Åkerfeldt1, it was observed that the yields became much smaller when the ground ...

To provide a potential approach, the research groups of Weihong Tan and Xue-Qiang Wang at the Hangzhou Institute of Medicine used phosphorothioate backbone modification to enhance the recognition ...

The Weihong Tan and Xue-Qiang Wang groups at Hangzhou Institute of Medicine (HIM, Chinese Academy of Sciences) have demonstrated the effectiveness of phosphorothioate backbone modification in ...