Gene transfer into the peritoneal cavity by nonviral methods may provide an effective therapeutic approach for peritoneal diseases. Herein, we investigated the feasibility and the effectiveness of ...

Drug delivery systems can alter drug clearance from the peritoneal cavity and drug toxicity profiles. For example, IP injection of cisplatin-loaded polymeric microspheres (100–200 µm, which ...

Gastric cancer that metastasizes to the peritoneum, or the lining of the abdominal cavity, has a very poor prognosis and is ...

The ratios of drug AUC in the peritoneal cavity and AUC in systemic blood are 12 for cisplatin, 10 for carboplatin, 65 for melphalan, 65 for etoposide, 75 for mitomycin C, 367 for 5-fluorouracil ...

Background: A spontaneous immune response to ovarian cancer improves survival, but tolerant features of the peritoneal (IP) cavity contribute to local immune suppression and tumor immune escape.

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the ...

Evidence has been secured that when colon bacilli or streptococci are injected in large numbers into the peritoneal cavity of dogs or rabbits, they begin to enter the blood through the thoractic duct ...

Prognostic significance of free peritoneal tumor cells in the peritoneal cavity before and after neoadjuvant chemotherapy in patients with gastric cancer undergoing a potentially curative resection.

Neoantigen (tumor-specific antigen) mRNA-based vaccines induce progenitor‑exhausted T cells that support anti‑PD‑1 therapy, leading to enhanced antitumor efficacy against gastric cancer, which has ...

Peritoneal cancer is a form of cancer that affects the peritoneum, a thin layer of tissue that lines the abdominal cavity and internal organs. It is not common, with around about 7 cases occurring ...

Takashi Kitagawa ¹, Hideaki Nakata ², Shingo Kimura ¹, Sachiko Tsuji ³, Thermoconservation mechanisms inferred from peritoneal cavity temperature in free-swimming Pacific bluefin tuna Thunnus thynnus ...