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Osteoblastic lesions were seen in 23% of the cases, and they all showed different patterns.
Extensive osteoblastic metastases were also seen in roentgenograms of the skull, vertebras and pelvis (Fig. 2). No abnormal intracranial calcifications were noted.
Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway.
Osteoblastic syndecan-2 affected osteogenic precursor apoptosis. RT-qPCR analysis of mRNA expression of Bcl2 (a) and BAX (b) in BMCs or bone extracts from 4-month-old mice.
The authors further reported that among the 32 patients included in the study, 25 were classified into the osteoblastic group, with a mean age of 73 ± 6.6 years, while the remaining 7 were placed ...
Downregulation of PTHrP and RANKL inhibited osteoclastogenesis and proliferation of stromal/osteoblastic cells. Release of TGF-a and IGF from the bone matrix was blocked. Vinorelbine destabilized MT ...
Morphology of bone metastases was osteolytic, osteoblastic and mixed in 32%, 25% and 22% of cases, respectively, with 21% of cases of unknown morphology.
New Rochelle, NY, March 27, 2019-Bone fracture healing can be augmented with the application of pulsed electromagnetic fields (PEMFs), but a consensus regarding idealized conditions is lacking. A ...
For osteoblastic differentiation, the medium was removed 6 h after transfection and substituted for fresh medium containing 10% FBS and 100 ng ml −1 BMP-2 (R&D Systems, Minneapolis, MN, USA).