核衣壳蛋白（Nucleocapsid，N蛋白）作为冠状病毒的主要结构蛋白之一，在新冠病毒的生命周期中起着至关重要的作用。它可以与病毒RNA形成核糖核蛋白 ...

Rabies is notoriously difficult to treat once symptoms begin, and that challenge starts at the molecular level. Unlike many ...

Nucleocapsid antigen samples were higher in people with COVID-19 illness who died or needed intubation within 30 days of sampling compared to those who survived or did not need intubation.

编辑推荐： 为解决SARS-CoV-2变异株逃逸现有疫苗保护的问题，研究人员通过免疫信息学 (immunoinformatics)和反向疫苗学 (reverse vaccinology)技术，设计了一种靶向刺突蛋白 (spike)和核衣壳蛋白 (nucleocapsid)的多表位mRNA疫苗。该疫苗覆盖99.99%全球人群，能诱导强烈的B细胞 (BCR)和T细胞 ...

A recent manuscript demonstrates that single point mutations in the specific region of the Nucleocapsid (N) protein, position 199-205, substantially increase the infectivity of the virus, in some ...

Trial participants who were given the placebo, rather than the vaccine, and became infected during the trial were found to have significantly higher levels of the neutralizing anti-nucleocapsid ...

Their findings reveal that nucleocapsid-based vaccines are effective in preventing SARS-CoV-2 infection in distal organs, such as the brain. The study is currently available on the bioRxiv ...

A recent paper by Syed et al. demonstrates that mutations in the Nucleocapsid (N) protein, one of the four structural proteins in SARS-CoV-2 in addition to the Spike protein, plays a critical role ...

“The nucleocapsid is the most abundant protein in the virus and it’s highly immunogenic — able to produce an immune response. Thus, our new findings may facilitate the development of new antiviral ...

The nucleocapsid’s cylindrical shape is made up of three layers; each layer plays a different role as the virus replicates in host cells. Before LJI’s imaging studies, the existence of the ...

Nucleocapsid (A) and spike (B) coding genes of Coronavirus genus were compared with CTLD genes of human (homo sapiens) and mouse (mus musculus) species (C, D).