The nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels, the activity of which modulates many neurotransmitter systems. They are therefore therapeutic targets for the ...

A role for β2* nicotinic receptors in a model of local amyloid pathology induced in dentate gyrus. Neurobiology of Aging, 2016; 46: 221 DOI: 10.1016/j.neurobiolaging.2016.06.005 ...

"Nicotine changes how nicotinic receptors are grouped on brain cells." ScienceDaily. ScienceDaily, 13 February 2017. <www.sciencedaily.com / releases / 2017 / 02 / 170213152302.htm>.

Bionomics has collaborated with MSD to identify novel α7 nAChR PAMs suitable for the treatment of cognitive disorders like Alzheimer’s DiseaseBased on the learnings from Bionomics’ candidate ...

Study: An experimental test of the nicotinic hypothesis of COVID-19. Image Credit: Nhemz/Shutterstock A new study published in PNAS Physiology confirmed that the SARS-CoV-2 spike protein does not ...

The results also intrigued researchers because alpha7 nicotinic receptors are genetically altered in schizophrenia, a disease marked by disorganized thinking. “Prefrontal networks allow us to form and ...