Autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) is caused by postnatal arginine vasopressin (AVP) deficiency resulting from mutations in the AVP gene encoding the AVP pre ...

Diabetes insipidus is a clinical syndrome characterized by the excretion of abnormally large volumes of dilute urine (polyuria) and increased fluid intake (polydipsia). This Review focuses on the ...

Studies of neurohypophyseal function were performed in 16 patients at least three weeks after operation, when permanent postoperative levels of water excretion had become established.

The same neurohypophyseal hormone, oxytocin, is responsible for both the physiological and behavioral changes, but the site of action is different.