Three neuroblastomas and cell line SK-N-SH express both the wild-type and mutated Phox2B alleles. Oligo dT-primed cDNA of tumours N129, N511 and N532 and cell lines LAN-1 (control) and SK-N-SH ...

Neuroblastomas are characterized by 1p deletions, suggesting that a tumor suppressor gene (TSG) resides in this region. We have mapped the smallest region of deletion (SRD) to a 2 Mb region of ...

For over a century, researchers have noted that neuroblastomas exhibit diverse and often dramatic clinical behaviors (Figure 1). (For a timeline of the major advances in neuroblastoma research ...

Of 340 eligible participants, 190 underwent resection, 57 were treated with chemotherapy, and 93 were observed with gross residual tumor. Of those 93 patients with unresected tumors, spontaneous ...

These kinds of neuroblastomas can be classified into three distinct subgroups, each demonstrating unique prognostic implications and varying vulnerabilities to investigational therapies." ...

City of Hope. "Fighting neuroblastomas by blocking DNA replication, repair." ScienceDaily. ScienceDaily, 16 April 2014. <www.sciencedaily.com / releases / 2014 / 04 / 140416101339.htm>.

What sounds contradictory at first glance, namely firing a tumor with a growth factor, makes sense in neuroblastoma. Neuroblastoma is a tumor of the peripheral nervous system and the most common solid ...

The study, published today (5 February 2021) in Science Advances, sought to understand why neuroblastomas range in severity, with some easy to treat and others having relatively low five-year survival ...

Children who develop neuroblastomas, a rare form of cancer which develops in nerve cells, may benefit from receiving certain anti-tumor drugs as well as chemotherapy, a new trial has found.

Neuroblastomas have a wildly varied spectrum of clinical behavior that ranges from spontaneous regression to progressive disease and metastasis, report Drs. Yu-Feng Guo and Shi-Cang Yu.

Because of their neuronal origin, neuroblastomas synthesize and release neuropeptide Y (NPY), a small protein normally secreted from mature nerves. In previous research, Kitlinska and her ...