The genes that code for the transporters that are responsible for monoamine uptake were identified in the early 1990s. Monoamine transporters have been shown to be involved both in the regulation ...

Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and selectively inhibits monoamine oxidase type B (MAO-B). Rasagiline demonstrates complete and selective ...

Monoamine oxidase inhibitors (MAOIs) were the first medications approved for the treatment of depression symptoms and are also used to treat several other medical conditions, such as Parkinson's ...

THE enzyme monoamine oxidase (monoamine : O 2 oxido-reductase (deaminating), EC 1.4.3.4) (MAO) is likely to be concerned in the metabolism of known or suspected central nervous system transmitters ...

Neurotransmitters are key for synaptic transmission at axon terminals, but their transport modalities remain debated. This ...

Am J Health Syst Pharm. 2006;63(10):915-928. Results of this study suggest that adjunctive rasagiline significantly reduces off time with efficacy similar to that observed by adding entacapone to ...

Depression rates, which were already on the rise before the pandemic, appear to be higher than ever. One estimate from the World Health Organization (WHO) puts the global increase of people diagnosed ...

Both Adzenys and Adderall are stimulant-based drugs that target neurotransmitters in the brain, but there are some ...

Do you sometimes get a headache after you eat? You could be consuming foods high in tyramine, which can trigger migraine attacks in some people.

Ayahuasca, an herbal decoction used ancestrally by Amazonian Indians, improves the health status of people who have followed ...

Together, the findings suggested that 17α-estradiol extensively reshaped the cell populations, cellular communication, neuropeptide secretion, and neural synapse activity in aged hypothalamus, which ...

NBI-1065890 is commercialized by Neurocrine Biosciences, with a leading Phase I program in Psychiatric Disorders.