RDX-002, Response Pharmaceuticals’ lead candidate, is an investigational first-in-class, potent, selective, and gut-specific small molecule inhibitor of intestinal microsomal triglyceride ...

All but one of the six solubilities measured were within fivefold of the ADMET Predictor estimated value, and the average predictive errors for rat and human microsomal clearance, also estimated ...

An antithyroid microsomal antibody test is also called a thyroid peroxidase test. It measures antithyroid microsomal antibodies in your blood. Your body produces these antibodies when cells in ...

The microsomal enzyme system can be activated by using an inducer drug that can bind to the receptor present in the cytoplasm or nucleus. This receptor-inducer complex then travels to the nucleus ...

Kathleen Randall, Shun Wen Cheng, Anne Therese Kotchevar, Evaluation of surfactants as solubilizing agents in microsomal metabolism reactions with lipophilic substrates, In Vitro Cellular & ...

The microsomal pellet contained plasma membrane, golgi, endoplasmic reticulum, mitochondria, lysosomes, and all other membrane-bound vesicles separated from soluble cytosol 14.

The microsomal triglyceride transfer protein is responsible for transferring triglycerides onto apolipoprotein B within the liver in the assembly of very-low-density lipoprotein (VLDL), the ...

Cytoplasmic and microsomal membrane fractions were isolated from root tips (first 5 mm) and the adjacent 2-cm region of roots of both cultivars. When root cytoplasmic proteins were analyzed by sodium ...

Microsomal triglyceride transfer protein (MTP) plays a critical role in the assembly of lipoproteins. The aim of this study was first to seek new MTP gene variants and then to verify whether MTP ...

Cite this: Inhibition of Microsomal Triglyceride Transfer Protein Alone or With Ezetimibe in Patients With Moderate Hypercholesterolemia - Medscape - Aug 01, 2008.