2022年11月10日，我院莫玮教授团队在Neuron杂志上发表了题为 “Microglial Piezo1 senses Aβ fibrils stiffness to restrict Alzheimer’s disease”的研究成果，揭示了小胶质细胞通过机械力受体Piezo1感知纤维化Aβ硬度而激活，并显著改善AD相关病理变化 ...

Increasing CD11c+ microglial subsets in the spinal dorsal horn by intrathecal treatment of interleukin-4 alleviate pain hypersensitivity caused by nerve injury.

Microglial responsiveness to CSF1R inhibition was determined by measuring the number of remaining immunolabeled microglia in different brain regions of male and female mice after PLX treatment.

Nature：阻断蛋白CD22有望让衰老大脑返老还童 CD22 α-突触核蛋白 β-淀粉样蛋白 吞噬作用 小胶质细胞 抗体 海马体 认知 髓磷脂 来源：本站原创 2019-04 ...

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

The gene scene To date, nearly a dozen genes involved in immune and microglial function have been tied to Alzheimer's. The first was CD33, identified in 2008.

Microglial cells are the maintenance workers of the central nervous system (CNS), protecting against pathogens and pruning damaged neurons to help the brain maintain homeostasis. Considered immune ...

Abnormal microglial energy metabolism in AD. Translocation of Aβ into microglial mitochondria by the outer membrane translocase (TOM) impairs mitochondrial function and inhibits phagocytosis.

"Regulating microglial activity may reduce inflammation in neurodegenerative diseases." ScienceDaily. ScienceDaily, 17 October 2018. <www.sciencedaily.com / releases / 2018 / 10 / 181017111016.htm>.

Opinion Published: 11 November 2014 Microglial and macrophage polarization—new prospects for brain repair Xiaoming Hu, Rehana K. Leak, Yejie Shi, Jun Suenaga, Yanqin Gao, Ping Zheng & Jun Chen ...

The microglial numbers plummeted 50 percent within three days and by 90 percent after a week. The microglia expressed apoptotic proteins, indicating they were dying, and by two to three weeks of ...