In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. Subscribe to our ...

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, ...

Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates ...

Summary: Unlike most tissues, the retina doesn’t summon neutrophils—the body’s typical first responders—when injured. Instead ...

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

A new study shows how a type of cells called microglia contribute to the slowdown of neuron activity seen in Alzheimer's disease. The study found that microglia that express the APOE4 gene, one of ...

When microglia go haywire, they destroy synapses and neural connections in the brain that affect mood and behavior. Calming them down could pay off for various disorders.

Left: An immune brain cell (microglia) in a human brain. Right: Microglia in the novel organoid model with a human-brain-like environment. The cells are almost indistinguishable. [Salk Institute] ...

Microglia have been found to clear brain debris, such as amyloid plaques in Alzheimer’s disease (AD) and damaged myelin in multiple sclerosis (MS). The current study demonstrated that when a molecule ...

Notably, microglia bearing the G2019S mutation in the LRRK2 kinase that causes Parkinson’s disease fumbled these hand-offs. In all, the findings suggest that microglia share the burden of α-synuclein ...