One of the major limitations of cancer gene therapy using recombinant human adenovirus (Ad) is rapid Ad inactivation from systemic delivery. To eliminate this, biotin-coated ultrasound contrast ...

Microbubbles were originally developed to help improve ultrasound imaging. However, being able to "pop" oxygen-filled microbubbles within tumors using beams of ultrasound presented researchers ...

The researchers showed that bursting the microbubbles with ultrasound immediately prior to irradiation almost tripled the radiosensitivity of the tumour. It also nearly doubled survival times in the ...

Microbubbles are contrast agents for ultrasound. When the microbubbles are first injected, ultrasound scanners are used to image the tumor and localize where the microbubbles accumulate/distribute.

Single-beam acoustical trap To test their technique, the researchers used a single-beam acoustical trap to manipulate microbubbles in three dimensions through three-centimetre-thick layers of elastic ...

Popping microbubbles help focus light inside the body Date: December 2, 2015 Source: California Institute of Technology Summary: A new technique that uses gas-filled microbubbles for focusing ...

Ultrasound in combination with microbubbles is currently the only method to penetrate the blood-brain barrier in a way that only affects conditions locally and that does not destroy the tissue.

Ordinary microbubbles have been approved by the Food and Drug Administration and in clinical use for several years now. But such microbubbles, a kind of ultrasound “contrast agent,” have only been ...

The gas-filled microbubbles are encapsulated by thin protein shells and have an acoustic refractive index--a property that affects how sound waves propagate through a medium--different from that ...