Iridoid gene discovery We previously reported the assembly of CathaCyc, a C. roseus metabolic pathway database based on Illumina HiSeq2000 RNA sequencing data 16. The data set was derived from C ...

The altered iridoid mixture corresponding to damaged leaves promoted a much more prolonged response. “It was easy to speculate that the response duration would increase with the amount of iridoid.

John A. Pickett, Independent evolution of the iridoid biosynthetic pathway in plants and insects, Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 48 ...

Iridoid synthase reduces the precursor, converting it into a highly reactive enol that it then releases. The synthase doesn’t catalyze the cyclization step, the researchers found.