The method, termed “Hyperpolarized MRI”, will allow imaging and visualization of key metabolic substrates in the heart and other organs (e.g., kidney, liver) via hyperpolarization of nuclear spins of ...

The hyperpolarized fumarate is converted into malate by the addition of a heavy water molecule. This conversion eliminates the symmetry of the molecule, rendering it magnetic and detectable.

On December 23, 2022, the FDA granted approval for Polarean’s first drug device combination product, XENOVIEW TM (xenon Xe 129 hyperpolarized). 129 Xe MRI is also currently being studied for ...

Hyperpolarized 13C imaging was used to monitor BAT metabolic conversion of pre-polarized [1-13C] pyruvate in rats during baseline and norepinephrine (NE)-stimulated conditions.

Hyperpolarized MRI is based on the premise that cancer cells use and metabolize nutrients differently, and often at a faster rate, than normal cells do. Prior to the procedure, the molecules of a ...

Metabolic MR imaging using hyperpolarized 13 C-pyruvate provides real-time assessment of pyruvate-to-lactate conversion, a process enhanced by PI3K/mTOR overactivation. We performed first-ever ...

The FDA has approved xenon Xe 129 hyperpolarized, or Xenoview, to use along with MRI to analyze lung ventilation among adults and children aged 12 years and older, according to a manufacturer ...

A new diagnostic technique called hyperpolarized MRI provides a clear image of the brain’s metabolic activity. This can give important clues about whether a treatment is working in a shorter time ...

Cite this: A Noble Cause: Hyperpolarized Noble Gas MRI to Revolutionize Lung Imaging? - Medscape - Apr 01, 2016.

The code is effective as of October 1, 2023Durham, NC, Aug. 29, 2023 (GLOBE NEWSWIRE) -- Polarean (AIM: POLX), a commercial-stage medical device leader in advanced MRI scanning of the lungs ...