支气管肺发育不良 (Bronchopulmonary dysplasia, BPD)作为早产儿最常见的慢性肺部疾病，其发病机制与高氧 (Hyperoxia)诱导的氧化应激密切相关。跨膜蛋白TMEM106B作为自噬 (Autophagy)调控的关键分子，在BPD患者中表达显著升高 (ROC曲线AUC=0.7122)。新生大鼠模型证实，高氧刺激可促进巨噬细胞 ...

NO prevents hyperoxia-induced NF-κB consensus sequence binding of nuclear proteins. HPMEC were exposed to 24 h of room air, hyperoxia, NO plus hyperoxia, NO alone, or TNF-α (4 h). A ...

Dolma, K., et al. (2019) Effects of Hyperoxia on Alveolar and Pulmonary Vascular Development in Germ Free Mice.

Hyperoxia in the Treatment of Traumatic Brain Injury and Stroke Christos M. Tolias, MBBS, PhD, FRCS (Engl), FRCS (SN) Disclosures Transfusion Alter Transfusion Med. 2010;11 (4):148-155. 0 ...

The Society for In Vitro Biology (SIVB) was founded in 1946 as the Tissue Culture Association to foster exchange of knowledge of in vitro biology of cells, tissues and organs from both plant and ...

References Mach WJ, et al. Consequences of hyperoxia and the toxicity of oxygen in the lung. Nurs Res Pract. 2011; 2011: 260482. Applegate RL 2nd, Dorotta IL, Wells B, Juma D, Applegate PM.

Background: Helium-hyperoxia (HH) reduces dyspnea and increases exercise tolerance in patients with COPD. We investigated whether breathing HH would allow patients to perform a greater intensity ...

Pryor KO, Fahey TJ III, Lien CA, Goldstein PA. Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population. A randomized controlled trial. JAMA ...

Gauthier C.J., Hoge R.D. (2012) Magnetic resonance imaging of resting OEF and CMRO2 using a generalized calibration model for hypercapnia and hyperoxia, NeuroImage, 60 (2): 12121225 Gauthier C.J., ...