We describe a series of cases of extreme hypercholesterolemia mediated by lipoprotein X in patients with chronic graft-versus-host disease of the liver after an allogeneic bone marrow transplant ...

The aim of this study is to evaluate the effects of hypercholesterolemia in thoracic aorta (TA), mesenteric artery (MA), renal artery (RA), and corpus cavernosum (CC) isolated from cholesterol-fed ...

2022年6月18日，中国科学院上海药物研究所南发俊课题组和李静雅课题组合作在Acta Pharmaceutica Sinica B上发表文章“Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia”，在高胆固醇血症靶向治疗策略中取得重要进展 ...

-- NewAmsterdam entitled to tiered double-digit percentage royalties ranging from the low double-digits to mid-twenties on net sales in the Menarini Territory and up to an additional €833 million upon ...

The FDA has approved a labeling update for Leqvio (inclisiran) allowing for first-line use in the treatment of hypercholesterolemia.

Diagnosis Hypercholesterolemia does not usually present with any symptoms and the only way to check for the condition is to perform a check of the blood cholesterol level, referred to as a lipid ...

Diagnosis typically involves a combination of clinical evaluation and genetic testing. Familial Hypercholesterolemia can be caused by mutations in the LDL receptor gene, APOB gene, or PCSK9 gene.

Summary This latest Pharmaceutical and Healthcare disease pipeline guide Hypercholesterolemia - Drugs In Development, 2022, provides an overview of the Hypercholesterolemia (Metabolic Disorders ...

Familial Hypercholesterolemia (FH) Market Outlook This section of the report includes the dynamics of market scenario for FH in the 7MM, i.e., the United States, EU5 (Germany, France, Italy, Spain ...

There has been some confusion about the number of people who have homozygous familial hypercholesterolemia. The FDA and ISIS/Genzyme said the condition affects about one in every million people.

This condition is known as Familial Hypercholesterolemia (FH), it is a genetic disorder that leads to abnormally high levels of low-density lipoprotein (LDL) cholesterol in blood and significantly ...

The first is tendon xanthomata, which causes yellowish, cholesterol-rich deposits to appear on the knuckles of you hands, knees or the Achilles tendon at the back of the ankle. Similarly, xanthelasmas ...