In this multicenter, randomized, controlled trial involving pediatric patients with heterozygous familial hypercholesterolemia, the PCSK9 inhibitor evolocumab, when added to statin therapy with or ...

Learn about the causes, symptoms, and treatment of heterozygous familial hypercholesterolemia, a disease that causes you to have very high cholesterol levels.

Heterozygous is a term used in genetics to describe when two variations of a gene, known as alleles, are paired at the same location (locus) on a chromosome. By contrast, homozygous is when there ...

Heterozygous hemochromatosis does not necessarily require any treatment. However, the gene can pass to children, which will mean they carry it as well.

Heterozygous familial hypercholesterolemia (HeFH) is a monogenic disorder that affects about 1 in 500 people, with a higher prevalence in certain subpopulations such as people of Quebecois, Christian ...

MANNHEIM, Germany — Contrary to expectations, individuals with familial hypercholesterolemia (FH) have rates of overweight and obesity that mirror the general population ― rates that appear to ...

Heterozygous Ikzf1H191R mice or Ikzf1del (ex3-ex4) mice (mice with a mutation that deletes three of the N-terminal zinc fingers) have a high incidence of T-cell leukemia. 20,34 In contrast ...

Heterozygous example In a heterozygous genotype, the two different alleles interact with each other. This determines how their traits are expressed. Commonly, this interaction is based on dominance.

Gregory Todd Jones, Reidar Hagtvedt, Marketing in Heterozygous Advantage, Journal of Business Ethics, Vol. 77, No. 1, Ethical Issues in the Biotechnology Industry ...

Lancelot Hogben, The Detection of Linkage in Human Families. II.--One Heterozygous Genotype Indeterminate, Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological ...