Rescue of glutaric aciduria type I in mice by liver-directed therapies. Science Translational Medicine, 2023; 15 (692) DOI: 10.1126/scitranslmed.adf4086 ...

据了解，戊二酸血症I型（Glutaric Acidemia Type I,GA-I），又称为戊二酸尿症（Glutaric Aciduria Type I），是一种罕见的常染色体隐性遗传性神经代谢性疾病 ...

L-2-hydroxyglutaric aciduria (L-2-HGA) is a rare neurometabolic disorder characterized by accumulation of L2-hydroxyglutarate (L-2-HG) due to mutations in the L2HGDH gene. L-2-HGA patients have a ...

Lai Jia Chi has Glutaric Acidemia Type 1 (GA1), a genetic disorder detected at age three after a severe fever, despite appearing healthy initially. GA1, if undetected, can cause brain damage ...

Taehee Han, Gi Bae Kim, Sang Yup Lee, Glutaric acid production by systems metabolic engineering of an L-lysine–overproducing Corynebacterium glutamicum, Proceedings of the National Academy of Sciences ...

A Korean research team led by Distinguished Professor Sang Yup Lee at the Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, applied systems ...

A new study summarizes over 30 years of clinical experience in the treatment and management of glutaric acidemia type 1 (GA1), a rare and potentially devastating metabolic disorder caused by ...

Glutaric acidurias are a group of organic acidurias, which have three main types. Each type results from different genetic changes that affect different metabolic enzymes. GA1 is the most common type.

Liam — who was diagnosed with glutaric aciduria type at just three months old — is non-verbal but attends a mainstream school and is due to go into secondary school in Killarney this year.

Production of 5-aminovaleric and glutaric acid by metabolically engineered microorganism Date: December 20, 2012 Source: The Korea Advanced Institute of Science and Technology (KAIST) Summary ...