The glomerular basement membrane (GBM) is a thin (250–400 nm) meshwork of extracellular matrix proteins that is an integral part of the glomerular filtration barrier. Most of the GBM is situated ...

Diseases that reduce the glomerular capillary surface area available for filtration or that alter the intrinsic permeability of the capillary wall reduce the glomerular filtration rate (GFR ...

When you think of hematuria, you think of a state in which your urine is mixed with red blood. However, the presence of ...

The FDA has approved Empaveli for the treatment of adult and pediatric patients aged 12 years and older with C3G or primary ...

The glomerular filtration rate (GFR) is considered to be the most important assessment of kidney function. In clinical practice, the total GFR, which is the sum of all the single-nephron GFRs, is ...

Updates on glomerular diseases from ASN 2023 include data from the NeflgArd trial examining Nefecon for immunoglobulin A nephropathy and the benefits of sparsentan as reported by two trials.

A glomerular filtration rate (GFR) test is a simple blood test that measures how well the kidneys are functioning. A doctor may order a GFR test to gauge kidney health. The kidneys are a pair of ...

Glomerular Disease: Symptoms Most patients present with swelling on their legs and around their eyes, excessive frothing in urine, high blood pressure and sometimes with decrease in urine production.

The glomerular filtration rate (GFR), the fluid volume filtered from the capillaries of the renal glomeruli into the Bowman’s capsule per unit time, is used for calculations of carboplatin ...

10. Coresh J, Turin TC, Matsushita K, et al. Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality. JAMA. 2014;311 (24):2518-2531.

Sex differences in kidney diseases have received limited attention. Research in this area is crucial for developing targeted ...