北京时间2024年12月5日，基础医学院洪登礼研究员团队在国际顶尖学术期刊Nature在线发表了题为“Fetal hepatocytes protect the HSPC genome via fetuin-A”的研究论文。该研究首次揭示了胚胎发育组织保护其干细胞基因组的机制，并证明该机制与发育疾病（如儿童肿瘤）的发生密切相关。本科研成果将为进一步 ...

Fetuin-A and osteoprotegerin (OPG) are arterial calcification regulators, which are related to cardiovascular survival in hemodialysis patients. We hypothesized that a balance of these ...

而姜黄素虽然表现出抗炎抗氧化特性，但对fetuin-A这种与胰岛素抵抗密切相关的肝源性蛋白的调控作用有限。 特别值得注意的是，研究首次报道了fetuin-A与Sirtuin 1在T2DM患者中的负相关关系，为理解代谢性炎症的分子机制提供了新线索。

Association of Serum Fetuin-A Levels With Mortality in Dialysis Patients Hermans MM, Brandenburg V, Ketteler M, et al Kidney Int. 2007;72:202-207 ...

Fetuin-A leads to pathological changes of the kidney However, adipose tissue is not harmful per se. It can even have protective effects.

Higher fetuin-A levels were associated with a significantly lower risk of cardiovascular disease in the absence of type 2 diabetes (hazard ratio [HR], 0.93 per 0.1g/L higher fetuin-A).

Blocking fetuin-A from binding to the insulin receptor may be useful in the prevention or treatment of insulin-resistance. Researchers from the University of California at San Diego, and various ...

So it could tell us something about disease severity, but at this time we're not sure." Interestingly, there were no correlations between fetuin-A and IgG or IgM levels or indexes, she reported.