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扩展免疫荧光技术 (ExIF):基于深度学习的虚拟标记 ...
研究人员针对标准免疫荧光 (IF)成像仅能捕获约4种分子标记 (4-plex)的限制,开发了扩展免疫荧光 (ExIF)框架。该研究通过生成式深度学习虚拟标记技术,将精心设计但易于制备的4-plex免疫荧光面板整合为理论上标记数量不受限的统一数据集。在EMT模型验证中,ExIF显著提升了细胞表型分类、异质性流形 ...
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