该研究是一项全球随机、双盲、安慰剂对照研究，评估了Cyramza联合erlotinib（厄洛替尼）相对于安慰剂联合erlotinib一线治疗既往未接受治疗的转移性 ...

We used erlotinib-resistant A549 lung adenocarcinoma cells for initial characterisation of the role of mir-200c in erlotinib sensitivity and EMT induction.

Erlotinib also exhibited the time-dependent inhibition on CYP3A, regardless of the probe substrate used: the value of KI and kinact were 6.3 μmol/L and 0.035 min−1 for midazolam; 9.0 μmol/L ...

Brain metastasis (BM) is a leading cause of death from non–small-cell lung cancer (NSCLC). Reasoning that activation of the epidermal growth factor receptor (EGFR) contributes to radiation resistance, ...

Another study showed greater than 20% 6-month progression-free survival (PFS) in recurrent GBM after erlotinib treatment. 11 Another study noted erlotinib activity in particular in GBM with combined ...

Erlotinib is recommended as an option for treating locally advanced or metastatic non‑small‑cell lung cancer that has progressed in people who have had non‑targeted chemotherapy because of delayed ...

Therefore, erlotinib was again discontinued, and we administered 125 mg of aprepitant on day 1 after discontinuation and 80 mg of aprepitant on days 2 and 3, with the aim of treating the pruritus.

At the time of the manufacturer's original evidence submission, the marketing authorisation for erlotinib had not been granted and the population who would be covered by the marketing authorisation ...

Erlotinib demonstrated good clinical benefit with acceptable toxicity for the treatment of women with vulvar carcinoma, according to findings from a phase-2 trial.

Loss of heterozygosity predicted increased risk for oral cancer among patients with oral premalignant lesions, according to the results of a randomized clinical trial.Although loss of ...

Erlotinib was first approved more than a decade ago for the treatment of patients with advanced non-small cell lung cancer (NSCLC), following failure on at least 1 prior chemotherapy treatment.

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