Epitopes are then mapped by screening mAbs against these fragments using selective binding assays. The technique is relatively rapid, inexpensive, and compatible for mapping both linear and ...

Dominant linear epitopes were identified in the C-terminal domains of the S1 and S2 subunits (amino acids 558-569, 627-638, and 1148-1159) that have previously been associated with SARS-CoV-2 ...

The recognition of these epitopes by the cluster of differentiation 8 (CD8) + T-cell receptors (TCRs) is crucial to clear pathogenic infections and mounting a response to cancer immunotherapy.

Two dominant epitopes (E A and E B) have been identified in the α3 (IV) NC1 domain. 108–112 Both are inaccessible for antibody binding unless dissociation of the hexamer occurs (Figure 5).

CONCLUSION: Our data demonstrate that some MUC-1 epitopes are expressed on normal BM cells and particularly on cells of the erythroid lineage. Hence the application of anti–MUC-1 antibodies for ...

Sanofi and Kling Bio have entered into a partnership aimed at accelerating the discovery of neutralising antibodies. The ...

Using patient-derived B cells, Kling-Select facilitates the rapid detection of new antibodies and preserved viral epitopes.

By combining the Gaiha Lab’s expertise in T cell immunology with the Barzilay Lab’s pioneering work in AI, the team—led by co-first authors Jeremy Wohlwend, PhD, and Anusha Nathan, PhD—sought to ...