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Spatial deconvolution from bulk DNA methylation profiles determines ...
eITH 对肿瘤微环境免疫景观的影响:研究发现,肿瘤内遗传异质性(gITH)与 eITH 之间无显著相关性。 同时,eITH 与肿瘤浸润免疫细胞的特征存在关联,MeHEG 评分与基于甲基化的肿瘤浸润淋巴细胞评估方法(MeTIL)评分呈负相关,且与 CD8 + 肿瘤浸润淋巴细胞(TILs)的浸润密度呈正相关。
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