The covariate is assumed to have population frequency = 0.5. Distinct curves relate to the covariate ORs of 2, 5, 10 and 50.

Covariate-based affected relative pair linkage analysis using single point IBD probabilities and a general conditional logistic model was performed as implemented in GENIBD and LODPAL of S.A.G.E ...

Recurrent events data are frequently encountered in clinical trials. This article develops robust covariate-adjusted log-rank statistics applied to recurrent events data with arbitrary numbers of ...

The covariate-adjusted response adaptive (CARA) design has been shown to be better than traditional designs in terms of both ethics and efficiency. However, its mechanism for allocating subjects makes ...

The covariate (a pretreatment score) is included in the model for increased precision in determining the effect of drug treatments on the posttreatment count of bacilli. The following code creates the ...

Interactions between treatment and covariates, such as prognostic factors, in randomized oncology trials are important because they are essential ingredients of individualized cancer treatments rather ...

FDA released its final guidance concerning covariate adjustments in randomized clinical trials on May 30, 2023. The guidance, which applies to randomized, parallel group clinical trials for both drugs ...