Article Published: 26 October 2014 Covalent docking of large libraries for the discovery of chemical probes Nir London, Rand M Miller, Shyam Krishnan, Kenji Uchida, John J Irwin, Oliv Eidam, Lucie ...

A hydroquinone-embedded covalent organic framework (Tz-QH-COF) was designed to address photocatalyst instability in ...

It is weaker than a covalent bond and can be either inter- or intramolecular. New research suggests this neat differentiation doesn’t tell the full story.

Template-assisted synthesis dramatically improves the yield of functionalized oligophenylene cages, report researchers from ...

Covalent (irreversible) Bruton’s tyrosine kinase (BTK) inhibitors bind to the C481 residue of BTK and block the ATP-binding pocket, thereby preventing catalytic activity. Despite excellent ...

Jaypirca led to better response rates than Imbruvica in some previously treated patients with chronic lymphocytic leukemia or ...

Novartis is serving up $60 million to partner with Matchpoint Therapeutics in hopes of getting an oral covalent inhibitor ...

Matchpoint Therapeutics said that it has signed an exclusive option and license agreement with Novartis (NYSE:NVS) to develop ...