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Cilostazol(Pletal India- Cilodoc ) generic is a phosphodiesterase type 3 inhibitor, prescribed for intermittent claudication. It works by improving blood flow to the legs.
Cilostazol inhibited insulin-induced and LXR-agonist-induced expression of SREBP-1c and its downstream targets, acetyl-CoA carboxylase and fatty acid synthase, in cultured hepatocytes.
Although dual antiplatelet therapy using cilostazol is associated with a lower risk of recurrent stroke in men, it has no significant benefit for women, a sub-analysis of CSPS.com results suggests.
When cilostazol is given orally, its plasma concentrations reach a maximum after 3 to 4 hours, and the plasma concentration is not altered by oral administration twice a day.
SAN DIEGO — The most quoted research publications are those that address clinically frustrating scenarios for which we have no answer. Charles Laham, MD, FSCAI, and colleagues attempted to ...
Cilostazol is a direct arterial vasodilator and it also inhibits platelet aggregation. Cilostazol has a UK marketing authorisation for the ‘improvement of the maximal and pain-free walking distances ...
The antiplatelet drug cilostazol (which prevents the blood from clotting) works as well as, and might be better than, aspirin in helping to prevent a secondary stroke in Asian patients, but with ...
In patients with femoropopliteal lesions, additional treatment with cilostazol after implantation of a drug-eluting stent is associated with significantly lower restenosis rates at 1 year, ...
Cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease Technology appraisal guidance; ...
Cilostazol is associated with increased heart rate, and in the relatively high proportion of ACS patients in CILON-T, this side effect may have contributed to increased event rates. Importantly, the ...
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